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Manic Behavior Resulting From Left Frontal Closed Head Injury in an Adult With Fetal Alcohol Syndrome

Received July 7, 2006; accepted October 5, 2006. From Eastern Virginia Medical School Department of Psychiatry and Behavioral Sciences, Norfolk, VA. Send correspondence and reprint requests to David R. Spiegel, M.D., Eastern Virginia Medical School Department of Psychiatry and Behavioral Sciences, 825 Fairfax Ave., Norfolk, VA 23507. e-mail: spiegedr{at}evms.edu
©2007 The Academy of Psychosomatic Medicine

Closed head trauma has been associated with various neuropsychiatric sequelae, including mood disturbances such as depression and mania. Although mood disturbances can occur with injury to either hemisphere, mania has been primarily associated with right-side frontal lobe injury. We present a case of manic behavior after a closed head injury to the left hemisphere in an adult with preexisting fetal alcohol syndrome.

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